核心團隊

蔡瑞哲 博士/研發長

大同大學 材料博士

    現 職:

  • 潤霈生技股份有限公司 總經理/研發長
  • 禾祺銳生技股份有限公司 研發長
  • 中華尖端醫療產品發展協會 理事長
  • 慶騰精密科技股份有限公司(4354) 監察人
  • 雷德睦華醫藥科技 首席技術顧問(北京)
  • 義守大學醫學工程系 兼任助理教授
  • 大同大學材料工程學系所 兼任助理教授、系務諮詢委員
  • 醫學中心臨床計畫、大專院校國科會計畫等 共同主持人

    經 歷:

  • 大同大學98年度 傑出校友 (相關報導)
  • 極麗醫學美容旗艦診所 執行董事
  • 冠麟生技公司 研發長兼副總經理
  • 愛派司生技有限公司 市場行銷顧問
  • 國立陽明大學醫學院 博士後研究員
  • 康力德生技股份有限公司 研發部經理
  • 新揚行實業有限公司 市場行銷部經理
  • 訊聯生物科技股份有限公司 副研究員
  • 美瑞世生物科技股份有限公司 研發部經理
  • 中國紡織工業研究中心醫用纖維組 副研究員

    蔡瑞哲博士國內外相關著作:

  • Jui-Che Tsai, Tim-Mo Chen, and Horng-Chaung Hsu, “Superiority of Growth Factors-Rich Autologous Platelet Rich Plasma in Tissue Engineering Fields”, 2018 GCBME第三屆全球生物醫學工程研討會。
  • 蔡瑞哲“從傳統PRP到『新GPS活力幹細胞』技術介紹與『醫美、抗衰』領域應用分享”,2017、2018台灣醫抗衰老暨微創美容交流學會。
  • Jui-Che Tsai, Tim-Mo Chen, and Li-Wei Chou, “Superiority of Growth Factors-Rich Autologous Platelet Rich Plasma in Different Clinical Applications”, 2017 International Symposium of Materials on Regeneration Medicnine.
  • Yi-Hsuan Lee, Hsi-Chin Wu, Chia-Wei Yeh, Chen-Hsiang Kuan, Han-Tsung Liao, Horng-Chaung Hsu, Jui-Che Tsai, Jui-Sheng Sun, and Tzu-Wei Wang, “Effect of platelet-rich plasma mixed with a plomeric bone fillingmaterial on sinus follr augmentation in rabbits”, Acta Biomaterialia 63 (2017) 210–226.
  • 吳書璇、許弘昌、陳佳君、郭書瑞、蔡瑞哲、方旭偉 “成人高濃度血小板血漿對軟骨細胞生長評估”,中華民國骨科醫學會 106年度第72次春季聯合學術研討會。
  • 吳書璇、許弘昌、陳佳君、郭書瑞、蔡瑞哲、方旭偉 “Assessment of adult blood-derived platelet-rich plasma for chondrocyte cell proliferation”, 2017年台灣再生醫學學會學術研討會。
  • Ching-Li Tseng, Guang-Wei Chang, Kuang-Ling OU, Wei-Ting Chou, Te-Hsing Wu, Hsu-Wei Fang, Jui-Che Tsai, and Tim-Mo Chen, 'Cranioplasty Using a Novel Osteoconductive Scaffold and Platelet Gel", Annals of Plastic Surgery 76 (2016) S125-S129.
  • Thierry Burnouf, Jui-Che Tsai, and Tim-Mo Chen, “Clinical application of platelet-derived biomaterials in regenerative medicine: experience in the use of allogeneic or autologous platelet gels”, WCPRM 2014.
  • 許弘昌、蔡瑞哲、葉明龍 “The use of platelet-rich plasma (PRP) in the treatment of OA: hype or hope?”,中華民國骨科醫學會103年度第67次聯合學術研討會。
  • 許弘昌、洪志鴻、蔡瑞哲 “Clinical superiority and correlation of autologous PRP and growth factors concentration for cartilage regeneration and sport medicine therapy”,中華民國骨科醫學會103年度第66次春季聯合學術研討會。
  • Huan-Ju Lai, Chen-Hsiang Kuan, Hsi-Chin Wu, Jui-Che Tsai, Tim-Mo Chen, Dar-Jen Hsieh, Tzu-Wei Wang, “Tailored design of electrospun composite nanofibers with staged release of multiple angiogenic growth factors for chronic wound healing”, Acta Biomaterialia 10 (2014) 4156–4166.
  • Ching-Li Tseng, Po-Chih Hsu, Lin-Gwei Wei, Te-Hsing Wu, Li-Han Shen, Guang-Wei Chang, Hsu-Wei Fang, Jui-Che Tsai, Yi-Ching Shen, Chi-Chang Wu and Tim-Mo Chen, “Effect of platelet-rich plasma mixed with a plomeric bone fillingmaterial on sinus follr augmentation in rabbits”, Biomedical Engineering: Applications, Basis and Communications, Vol. 25, No. 5 (2013).
  • Jui-Che Tsai, Horng-Chaung Hsu, “Clinical superiority of growth factors-rich autologous PRP for cartilage regeneration and sport medicine therapy”,中華民國生醫材料及藥物制放學會 2013 年會暨研討會。
  • Yuan-Sheng Tzeng, Shou-Cheng Deng, Chih-Hsing Wang, Jui-Che Tsai, Tim-Mo Chen, and Thierry Burnouf, “Treatment of Nonhealing Diabetic Lower Extremity Ulcers with Skin Graft and Autologous Platelet Gel: A Case Series”, BioMed Research International, Volume 2013.
  • Tim-Mo Chen, MD, Yuan-Sheng Tzeng, MD, Jui-Che Tsai, PhD, and Thierry Burnouf, PhD, “Single-Donor Allogeneic Platelet Fibrin Glue and Osteoconductive Scaffold in Orbital Floor Fracture Reconstruction”, Annals of Plastic Surgery & Volume 70, Number 3, March 2013.
  • Jui-Che Tsai, Ph.D, “Clinical superiority of growth factors-rich autologous PRP for cartilage regeneration and sport medicine therapy”, Taiwan Arthroscopy and knee Scoiety International Symposium on Arthroscopic Cartilage Surgery and Related Research, March 2013.
  • Tim-Mo Chen, Jui-Che Tsai, and Thierry Burnouf, “Reconstruction of orbital floor fracture using osteoconductive scaffold and single-donor allogeneic platelet fibrin glue”, Annals of Plastic Surgery.
  • Han-Tsung Liao, Chien-Tzung Chen, Chih-Hao Chen, Jyh-Ping Chen, and Jui-Che Tsai, “Combination of Guided Osteogenesis With Autologous Platelet-Rich Fibrin Glue and Mesenchymal Stem Cell for Reconstruction of Mandibular Defects in Canine Model”, The Journal of Trauma, Injury, Infection and Critical Care, Accepted for publication April 2, 2010.
  • Tim-Mo Chen, Jui-Che Tsai, and Thierry Burnouf, “A Novel Technique Combining Platelet Gel, Skin Graft, and Fibrin Glue for Healing Recalcitrant Lower Extremity Ulcers”, Dermotologic Surgery, Vol. 36, 1-8, 2010.
  • Shyh Ming Kuo, Li-Chun Lin, Pei-Leun Kang, Jui-Che Tsai, and Shwu Jen Chang, “Evaluation of Bone Growth Using Artificial Bone Substitute (Osteoset) and Platelet Gel Mixtures: A Preliminarily Study in Dogs”, Artificial Cells, Blood Substitutes, and Biotechnology, 37: 78-84, 2009.
  • Jui-Che Tsai, Shwu Jen Chang, Ioannis Manousakas, Tim-mo Chen, and Shyh Ming Kuo, “A Novel TGD Device to Generate Therapeutic Platelet Glue”, Biomedical Engineering: Applications, Basis and Communications, Vol. 19, No. 4, 225-229, 2007.
  • Tim-Mo Chen, Tsai Jui-Che, and Thierry Burmouf, “Cranioplasty Using Osteoconductive Scaffold and Platelet Glue”, The Journal of Trauma, Injury, Infection and Critical Care, Volume 65; Number 6, 2007.
  • Feng-Huei Lin, Jui-Che Tsai, Tim-Mo Chen, Ko-Shau Chen, Jen-Ming Yang e, Pei-Leun Kang, and Te-Hsing Wu, “Fabrication and evaluation of auto-stripped tri-layer wound dressing for extensive burn injury”, Materials Chemistry and Physics, 102, p.152-158, 2007.
  • Cheng-Hung Chou, Winston T. K. Cheng, Tzong-Fu Kuo, Jui-Sheng Sun, Feng-Huei Lin, and Jui-Che Tsai, “Fibrin glue mixed with gelatin/hyaluronic acid/chondroitin-6-sulfate tri-copolymer for articular cartilage tissue engineering: The results of real-time”, Journal of Biomedical Materials Research, Part A DOI 10.1002/jbm.a, p.758-767, 2007.
  • Ko-Shao Chen, Hong-Ru Lin, Su-Chen Chen, Jui-Che Tsai, and Yuan-An Ku, “Long Term Water Adsorption Ratio Improvement of Polypropylene Fabric by Plasma Pre-treatment and Graft Polymerization", Polymer J, Vol. 38, No. 9, p.1-7, 2006.
  • Jui-Che Tsai, Thierry Burnouf and Tim-Mo Chen, “Using TGD® device to produce autologous thrombin from plasma and its biomedical applications”, 3rd International Conference on Materials for International Conference on Advanced Technologies (ICMAT 2005- Singapore)
  • Tsai Jui-Che, Chen Chien-Tzung, Liao Han-Tsung, “Osteogenic effect of bone marrow mesenchymal setm cell (MSC) differentiated in osteoconductive autologous fibrin glue scaffold”, International Symposium on Recent Advance of Stem Cell Research.
  • 陳天牧、王先震、蔡瑞哲 “人體血小板膠於顱骨缺損重建之臨床應用”,中華民國整形外科醫學會九 十五年度月例會。
  • 陳天牧、王先震、蔡瑞哲 “人體組織膠及血小板膠在植皮手術之應用”,九十五年兒童燒燙傷年會。
  • Jaj Hsin Lu, Jui-Che Tsai, Shwu Jen Chang, Shyh Ming Kuo, "Fabrication of Hybrid Chitosan/PRP Regeneration Membranes," The 11th Biochemical Engineering Conference, Taiwan Symposium on Nanomedicine & Tissue Engineering, P1-055。
  • 陳克紹、陳素眞、蔡瑞哲、邱士華、伍德馨、陳家杰、陳天牧、林峰輝、林鴻儒 "The Applications of Radiation Exposure to Biomedical Artificial Dressing," The 11th Biochemical Engineering Conference, Taiwan Symposium on Nanomedicine & Tissue Engineering, P1-055.
  • 王婷儀、康沛倫、蔡瑞哲、張淑真、郭士民 “新穎幾丁聚醣/三鈣磷酸鹽/富血小板血漿微粒製備及 其為骨修補材料之應用”,2005 生醫材料暨藥物制放研討會。
  • 盧佳昕、蔡瑞哲、康沛倫、張淑真、郭士民 ‘Fabrication of Chitosan/PRP Complex Regeneration Membrane”,2005 醫工年會。
  • 蔡瑞哲、康沛倫、Thierry Bournuf “全自體血小板膠與纖維蛋白膠的製備及其動物實驗或臨床外科之應用”,2005 年生醫材料暨藥物制放研討會。
  • 王世典、劉建麟、蔡瑞哲 “異體血小板膠與纖維蛋白膠混合自體骨於脊椎手術上的融合評估”,2005年台灣脊椎外科醫學年會。
  • 陳弘毅、余榮光、蔡瑞哲 “富含成長因子的血小板纖維蛋白膠於脊椎融合手術上的應用與臨床報告”,2005 年台灣脊椎外科醫學年會。
  • 王世典、劉建麟、蔡瑞哲 “Evaluation of the Allologous Platelet Gel and Fibrin Glue Mixed with Auto Bone Substitute in Spinal Fusion”,2005 年中華民國運動醫學學會。
  • K.S. Chen , J.C. Tsai, F.H. Lin, T.M. Chen, T.H. Wu, C.C. Chen, “The Study of PP Nonwoven Composite Combined with Thermo-sensetive Hydro gel and Immobilized Biodegradable Material onto its surface”, Journal of Materials Science and Engineering, Vol. 35, No. 4, p.231-239, (2003).
  • Jui-Che Tsai, Ko-Shao Chen, Feng-Huei Lin and Tim-Mo Chen, “Fabrication of easily stripped off trilayer wound dressing – Properties analysis and biocompatibility evaluated”, ICMAT 2003, (Singapore).
  • 蔡瑞哲、陳克紹,林峰輝,陳天牧 “含明膠三層易剝離創傷敷料的生物適應性評估”,生醫材料及藥物制放研討會2003,p.131-132,(台灣大學)。
  • 陳克紹、劉家菁、蔡瑞哲、林鴻儒、林峰輝、陳天牧 “電漿改質多孔性Poly(Lactic-co-Glycolicacid)與細胞貼附特性之探討”,生醫材料 及藥物制放研討會2003,p.221-222,(台灣大學)。
  • Mu-Rong Yang, Ko-Shao Chen, Jui-Che Tsai, Ching-Cheng Tseng, Shuen-Fuh Lin, “Hydrophilic modification of pet nonwoven and the antibacterial activities evaluated”, Materials Science & Engineering C20, p.167-173, (2002).
  • Ko-Shao Chen, Jui-Che Tsai, Chih-Wei Chou, Mu-Rong Yang, Jen-Ming Yang, “Effect of additives on the photo-induced grafting polymerization of n-isopropylacrylamide gel onto the polymers surface”, Materials Science & Engineering C20, p.203-208, (2002).
  • Ko-Shao Chen, Mu-Rong Yang, Jui-Che Tsai, Feng-Huei Lin, Te-Hsing Wu, Chia-Chieh Chen and Tim- Mo Chen, “Composite of Polypropylene nonwoven combined with gelatin gel by glutaradehyde”, 39th Intern. Symp. On Macromolecules, p.916, July 7-12, 2002, Bejing, China.
  • 陳克紹,蔡瑞哲,楊木榮,伍德馨,陳家杰,陳天牧,林峰輝 “Study of easy stripped wound dressing non-woven contained biodegradable layer and their antibacterial activities”,p.31,2002,Jun. (Lung-Tan)。
  • 陳克紹,蔡瑞哲,楊木榮 “材料表面耐水洗抗菌改質技術”,成大創新育成中心技術發表。
  • Ko-Shao Chen, Jui-Che Tsai, Mu-Rong Yang, Chia-Chieh Chen, Te-Hsing Wu, Tim-Mo Chen and Feng-Huei Lin, “The study of PP nonwoven combined with biodegradable polymer hydrogels”,中醫暨醫學工程研討會2002,(逢甲大學)。
  • 陳克紹,楊禎明,李奇翰,蔡瑞哲 “電漿改質聚丙烯不織布表面固定幾丁聚醣水膠之研究”,中國材料科學2002年材料年會,(台灣大學)。
  • Jui-Che Tsai, Ko-Shao Chen, Mu-Rong Yang, Cheng-Cheng Tseng and Shuen-Fuh Lin, “HYDROPHILIC MODIFICATION OF PET NONWOVEN AND THE ANTIBACTERIAL ACTIVITIES EVALUATED”, ICMAT2001 SYMPOSIUM B: B10-20, p.82, (Singapore). 「此次發表獲教育部補助出席參加」
  • H. Wu, K. S. Chen, F.H. Lin, Y.G. Jen, J.C. Tsai and T.M. Chen, “Preparation of radiation-induced grafted tri-layer temporary wound dressing and cytotoxicity test observation”, 5th Asian Symposium on Biomedical Materials, p.126 (Hong Kong), Dec. 9-12, 2001, 5th Asian Symposium on Biomedical Materials.
  • Jui-Che Tsai, Ko-Shao Chen, Mu-Rong Yang, Ching-Cing Tseng, Shuen-Fun Lin, “Surface grafted vinyl quarternary ammonium salt onto PET nonwoven and their antibacterial activities”, p.157, (Hong Kong), Dec. 9-12, 2001.
  • 陳克紹,楊禎明,李奇翰,蔡瑞哲 “聚丙烯不織布表面接枝聚合改質及固定幾丁聚醣”,Proc. of the 24th ROC Polym. Sym. 2001,p.448-449,(台北)。
  • 楊振宇,蔡瑞哲,陳克紹,曾菁菁,林順富 “聚丙烯不織布表面固定含軟骨素生解性水膠”, Proc. of the 24th ROC Polym. Sym. 2001,p.446-447,(台北)。
  • 陳克紹,蔡瑞哲,楊木榮,伍德馨,陳家杰,黃亨通 “PP不織布表面改質及與明膠複合式暫時性燒燙傷敷料研製”,ROC - Japan Joint Symp. on Biomaterials and Controlled Release, Feb., 2001,p.90-92,(Taipei)。
  • 曾菁菁,林順富,陳克紹,蔡瑞哲,李奇翰,楊木榮,林峰輝,陳天牧 “PET不織布創傷敷料表面化學固定抗菌劑之研究”,ROC- Japan Joint Symp. on Biomaterials and Controlled Release, Feb.,2001,p.262-264,(Taipei)。
  • 陳克紹,李奇翰,蔡瑞哲,楊禎明 “表面化學固定幾丁聚醣於聚丙烯不織布之研究”,ROC- Japan Joint Symp. on Biomaterials and Controlled Release, Feb.,2001,p.271-273,(Taipei)。
  • Ko-Shao Chen, Jui-Che Tsai and Mu-Rong Yang, “Plasma treatment of polypropylene particles and surface-graft polymerization of water-soluble monomers for improving surface wettability”, 第一屆薄膜科技研討會,Apr.,2001,p.43-46,(Chung-Li)。
  • 陳克紹,蔡瑞哲,楊木榮,伍德馨,陳天牧,林峰輝 “ PP不織布表面交聯Gelatin水膠之複合敷料研究”,2001年中醫暨工程科技研討會,p.58,(Tai-chung)。
  • 陳克紹,楊禎明,李奇翰,蔡瑞哲 “化學交聯幾丁聚醣於電漿改質聚丙烯不織布表面之研究”,2001年幾丁質幾丁聚醣研討會,May 25,p.204-206,(Taipei)。
  • 陳克紹,蔡瑞哲,伍德馨,陳家杰,陳天牧,林峰輝 “輻射線照射在燒燙傷敷料之應用與展望”, 20001 Workshop on Material and Environmental Applications with Electron Accelerator Radiation, p.6-10,Aug.2,(Lung-Tan)。
  • 陳素真,蔡瑞哲,陳克紹,楊木榮,鄭淑蕙,劉有台 “聚丙烯不織布的光誘導接枝聚合水溶性單體”,Proc. of the 23th ROC Polym. Sym. 2000,p.17-18,(高雄)。
  • Ko-Shao Chen, Jui-Che Tsai, Mu-Rong Yang, Feng-Huei Lin, Te-Hsing Wu, Chia-Chieh Chen, Hen-Ton Huang and Tim-Mo Chen, “ Hydrophilic modification of PET Nonwoven and their Ag+ ion Antibacterial Activities”, Y2K ROC-Japan Joint Sympo. on Biomaterials and Controlled Release, p.365-368, (Hsinchu).
  • 陳克紹,蔡瑞哲,古燕華,楊木榮,林峰輝,伍德馨,陳家杰,蔡瑞燦,黃亨通,陳天牧 “高能活化PET不織布創傷敷料的表面滅菌性改質”,2000 Symp. On Isotope and Radiation Appl. and Joint Symp. of Nuclear Medicine, ROC and Chung Hua Nuclear Soc., p.8,(Lung-Tan),May19,(2000)。
  • 曾菁菁,林順富,陳克紹,蔡瑞哲,李奇翰,楊木榮,楊禎明,林鋒輝,陳天牧 “不織布創傷敷料的抗菌性及耐水洗性表面改質”,Proc.of the 2000 Annual Conf. of the Chinese Soc. for Materials Sci., ROC,(義守大學)。
  • Ko-Shao Chen, Jui-Che Tsai, Mu-Rong Yang, Feng-Huei Lin, Tzong-Zeng Wu and Ching-Hong Lien, “Surface modification of polypropylene particles by plasma and graft polymerization techniques”, THE 4th ASIAN SYMPOSIUM ON BIOMEDICAL MATERIALS, December 1-3, (Singapore), p.123, 1999.
  • 陳克紹,蔡瑞哲,古燕華,楊木榮,伍德馨,陳家杰,蔡瑞燦,林峰輝,連清宏 “表面接枝聚合研製暫時性的不織布創傷披覆材料”,1999年全球華人生醫材料暨藥物制放研討會,(Taipei),p.229-232,1999。
  • 蔡瑞哲, 陳克紹, 楊木榮,林峰輝 “聚丙烯粉體的電漿處理表面接枝聚合生醫改質” 1999年全球華人生醫材料暨藥物制放研討會,(Taipei),p.550-553,1999。
  • 陳克紹,蔡瑞哲,楊木榮,伍德馨,陳家杰,蔡瑞燦,林峰輝,連清宏 “以高能照射研製複合陶瓷粉水膠之研究”,1999年全球華人生醫材料暨藥物制放研討會,(Taipei),p.529-532,1999。
  • 蔡瑞哲,陳克紹,古燕華,楊木榮 “利用表面接枝處理研製生醫用之功能性不織布”,Proc.of the 1999 Annual Conf. of the Chinese Soc. for Materials Sci., ROC, (Hsinchu )。
  • J.C. Tsai, K.S. Chen, M.R. Yang, and C.Y. Huang, ”Surface-graft polymerization onto the PP particle for biomateeerial application”, Ann. Symp. of Biomedical Eng. Soc., ROC, p.481-482, (Yang-ming Univ., Taipei), 1998.
  • 蔡瑞哲、陳克紹、古燕華、楊木榮,*伍德馨、陳家杰、蔡瑞燦,林峰輝,連清宏 “利用表面接枝處理研製生醫用功能性不織布”,88年中國材料科學年會。

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